Month: February 2023

Human milk (HM) is considered the gold standard for the nutrition of infants, as it provides several dietary benefits to the mother-infant dyads for both the short and long term. HM comprises various types of cells including leukocytes and epithelial cells; however, data on cellular diversity and phenotypic characteristics during lactation are limited. Study: Metabolomic Diversity

A new brain connection discovered by University of California, Irvine researchers can explain how early-life stress and adversity trigger disrupted operation of the brain’s reward circuit, offering a new therapeutic target for treating mental illness. Impaired function of this circuit is thought to underlie several major disorders, such as depression, substance abuse and excessive risk-taking.

Rebecca Bart, PhD, member at the Donald Danforth Plant Science Center, and her colleagues from Washington University in St. Louis will be featured on a global stage at South by Southwest (SXSW) on March 11 at 2:30 PM at the JW Marriott, Austin Texas. SXSW is one of the most sought-after annual conferences in the

In a recent study published in the eBioMedicine, researchers examined the effect of serum levels of 20 amino acids in a mother during pregnancy on offspring birthweight in a two-sample summary data Mendelian randomization (MR) framework. Study: Causal effects of maternal circulating amino acids on offspring birthweight: a Mendelian randomisation study. Image Credit: SciePro/Shutterstock Background

Gestational diabetes and preeclampsia may be linked to slower biological development in infants, according to a new study led by USC. The research, published today in JAMA Network Open, found that newborns exposed to these two pregnancy complications were biologically younger than their chronologic gestational age. The infants’ biological or “epigenetic” age is based on

Our bodies are made up of 60,000 miles of complex pipes that play a vital role in transporting nutrients throughout our bodies, performing waste disposal, and supplying our organs with fresh oxygen and blood. Vascular malformations (VMs) are a group of rare genetic disorders that causes an abnormal formation of veins, arteries, capillaries, or lymphatic

Researchers at Children’s Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, which could open the door to numerous applications where robust presentation to the immune system is important, including cell therapy and immunization. The findings were published today in

The large influx of migrants and asylum seekers crossing the U.S.-Mexico border in the El Paso area has also resulted in a spike of medical emergencies. To provide necessary health care, Texas Tech University Health Sciences Center El Paso and Texas Tech Physicians of El Paso have collaborated with Doctors of the World USA to

More children and adolescents are identifying as transgender and offered medical treatment, especially in the US. But some providers and European authorities are urging caution because of a lack of strong evidence. In a new report from The BMJ Investigations Unit, Jennifer Block, investigations reporter, looks into the evidence base behind this surge in treatment.

In a recent study published in the journal PLoS ONE, researchers evaluate coronavirus disease 2019 (COVID-19) vaccine-associated composite serious adverse events following immunization (sAEFI) among five- to 17-year-old children in the United States to ascertain the composite reported risk associated with vaccination. Related Stories Study: Reported rates of all-cause serious adverse events following immunization with BNT-162b in

Scientists have wondered whether boys and girls think differently because their brains are different. A recent paper presents evidence that, indeed, girls do show meaningful differences in their brain circuits that could explain why their cognitive functions differ from those of boys. Study: Measures of Brain Connectivity and Cognition by Sex in US Children. Image

In a recent study published in the Morbidity and Mortality Weekly Report by the United States Centers for Disease Control and Prevention (CDC), researchers estimate the efficacy of the monovalent messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) in preventing symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in the pediatric population between the

For the first time, humans with newly diagnosed Type 1 diabetes, or T1D, have received two treatments called GABA and GAD that have shown promise in animal studies and in isolated human pancreas islets. This investigator-initiated clinical trial, published in Nature Communications, focused exclusively on children with recent onset T1D. Diabetes is a disease affecting

A new report, coauthored by several major pharmaceutical companies, reviews the current state of sterile oligonucleotide drug product processing. The article, which provides recommendations to aid in the evaluation and development of terminal sterilization processes, is published in the peer-reviewed journal Nucleic Acid Therapeutics. All marketed oligonucleotide products are delivered as sterile preparations for parenteral